Its a good piece but the main issue is the lack of contrast, between the yellow of the eyes and the skin mostly, some more contrast could be cool also in some other place, like the nose...
Try making the mouse's outline a dark grey only 1 pixel width (not one long line), and add contrast to the yellow part of the eyes (in relation to the white fur).
year of the rat, Year of the rat avatars, Year of the rat icons, Year of the rat pixel art, Year of the rat forum avatars, Year of the rat AOL Buddy Icons
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(My computer is at my fathers house, therefore only weekend use, yo)