That's a lot more animation than I usually expect to see for an image with that much detail, good work c:
I like it, the face seem to be lit from a computer-screen or laptop with some secondary lightning, which might come from an interior or exterior space, obviously artificial. The large single-colored field in the background might suggest an interior out of focus and spacious, rather than a back wall. This could have been helped by anti-aliasing the t-shirt gradually to those dark-torquise-greenish grays. Nice animation although it looks very much as a gesture rather than a genuine smile. *I didn't look at the reference file until after my comment*
I liked the way you did the mouth in first place.
There is no transfer of mass on the smile and the colors are way too dark.
Thank you, soon will upload more detailed facial animation, and add background