This week, create a mockup of an original digital board game. It can be a serious game or something utterly absurd.
Several existing examples here:
Puerte Rico
Lords of Waterdeep
Monopoly
Ticket to Ride
Small World
Canvas Size - Max 320 x 200. Either horizontal or vertical.
Colours - Max 22.
Transparency - No.
Animation - Optional.
The challenge thread will have all the challenge updates. The thread is also a great place to post your WIPs.
I was sitting with a couple of friends last week, discussing the possibility of using dominoes to create a sort of basic dungeon to play a primitive simple "RPG" for fun :)
Imma try and illustrate a concept if free time allows.
Damn, should've done the mutant thing. No inspiration for this week! 
Ooh, perfect excuse to pixel a chess thing. I probably won't finish it in time, but whatever.
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I would've participated if it could have been vertical but since both options are horizontal I ain't gonna.