This is my concept of what a perfect pixel-level Photoshop should look like, keeping it simple as MS Paint.
There is the Status Bar at the top; the Browser, Tool Box and Tool Options at the left; the Colors, Custom Pallette and Color Editor at the bottom; and Layers at the right. There is also a handy Calculator floating, it is very helpful when creating colors.
And finally the Work Place at the center, with indicators in the corners and centers of the canvas, details about the dimensions and the location of the cursor; also there is a line showing the status of the isometry (currently disabled), wich works like in AutoCAD.
"Super Paint" allows the users to create animated gifs too, but I was too lazy to draw the "Animation Window", so we are gonna say it is just hidden. Look for it in the View [Ver] menú :)